Employment Type: Permanent Position

Job Category: Research & Development

Department: Research & Development

Reports To (Position): Director of Preclinical Research

Job Number: 3096278

Position Overview:

We invite applications for the Manager of Preclinical Scientists position to join our client's dynamic team. The successful candidate will play a crucial role in designing, conducting, and analyzing preclinical studies essential for advancing innovative therapeutics. We are seeking someone with a solid foundation in pharmacology, toxicology, or a related field complemented by practical experience in executing preclinical studies. This is an exciting opportunity to contribute to cutting-edge research and make a meaningful impact.

Key Responsibilities:

• Design, manage, and execute in vitro and in vivo preclinical studies to evaluate drug candidates' efficacy, safety, and pharmacokinetics.
• Build and lead a laboratory team.
• Develop and validate animal models for various disease indications.
• Analyze and interpret preclinical data and prepare reports and presentations for internal teams and regulatory submissions.
• Collaborate with cross-functional teams, including pharmacology, toxicology, regulatory affairs, and clinical development, to align preclinical strategies with overall drug development goals.
• Manage relationships with biotech, pharmaceutical, and academic partners to conduct outsourced studies.
• Ensure compliance with regulatory guidelines (e.g., GLP, IACUC, AAALAC) and uphold best practices in animal welfare.
• Stay updated on advancements in preclinical research methodologies and regulatory expectations.

Qualifications:

• Ph.D. or M.S. in Immunology, Molecular Biology, Pharmacology, Toxicology, Biology, or a related field.
• 3+ years of experience in preclinical research within the pharmaceutical or biotechnology industry.
• Hands-on experience with in vivo models, including xenograft/syngeneic models, dosing, sample collection, and behavioral assessments.
• Experience with in-vitro assays including SPR, cell killing, tumor killing, ADCC assays
• Strong understanding of pharmacokinetics, toxicology, and safety assessment principles.
• Proficiency in data analysis and statistical tools.
• Excellent communication and organizational skills with the ability to work independently and in a team-oriented environment, along with managerial skills
• Must be able to interface externally with other organizations

Preferred Qualifications:

• Experience working in a Good Laboratory Practice (GLP) environment.
• Familiarity with regulatory requirements for Investigational New Drug (IND) applications.
• Knowledge of advanced imaging techniques, biomarker discovery, or computational modeling.

Benefits:

• Competitive salary and performance-based incentives.
• Comprehensive health, dental, and vision insurance.
• 401(k) with company match.
• Professional development and career growth opportunities.
• Collaborative and innovative work environment.