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Senior Research Associate/Associate Scientist, Antibody Discovery
Rockville, MD
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Job Details

Description


POSITION SUMMARY:

The Senior Research Associate in Antibody Discovery is responsible for advancing our antibody discovery programs by supporting and executing various laboratory-based activities, including phage display, antibody production, and downstream characterization. 


DUTIES AND RESPONSIBILITIES: 

  • Perform high-throughput screening of antibody libraries using techniques such as phage display.
  • Conduct binding and functional assays (e.g., ELISA, flow cytometry, SPR, BLI) to characterize antibody-antigen interactions.
  • Express, purify, and analyze antibodies using molecular biology, protein expression, and purification techniques (e.g., PCR, cloning, transient/stable transfection, chromatography).
  • Analyze experimental data and present findings to the team.
  • Maintain accurate and detailed laboratory records, including experimental procedures, results, and conclusions.
  • Contribute to the preparation of technical reports, presentations, and scientific publications.
  • Participate in project meetings and contribute to the design and planning of experiments.
  • Communicate effectively with team members and external collaborators.


EXPERIENCE AND QUALIFICATIONS:

  • Bachelor’s degree in Molecular Biology, Biochemistry, Immunology or related area is required. 
  • Master’s degree is preferred. 
  • A minimum of two years of hands-on laboratory experience in antibody discovery or a related field. Industry experience is a plus.


KNOWLEDGE, SKILLS AND ABILITIES:

  • Proficiency in molecular biology techniques (e.g., cloning, PCR, site-directed mutagenesis).
  • Experience with antibody screening and characterization assays (e.g., ELISA, flow cytometry, SPR, BLI).
  • Familiarity with protein expression and purification methods (e.g., mammalian, bacterial, or yeast expression systems).
  • Strong analytical and problem-solving skills.
  • Demonstrated aptitude for learning of and adhering to standard laboratory techniques and safety precautions.
  • Solid communication (written and verbal) skills regardless of the format (e.g., documents, public speaking situations, presentations, etc.). 
  • Excellent organizational, planning, and time management skills with the ability to manage multiple and often changing priorities and issues of varying complexity, while meeting time-sensitive deadlines and deliverables.
  • Attention to detail with demonstrated commitment to excellence and performance. 
  • Demonstrated propensity to be creative, collaborative, proactive, and self-motivated in the execution and completion of assigned tasks.  
  • Ability to work both independently and as an effective team member. 
  • Ability to execute complex experiments with limited guidance. 
  • Ability to identify issues and troubleshoot solutions.  
  • Solid data analysis skills. Sound knowledge of MS Excel. Knowledge of GraphPad Prism and SharePoint a plus. Basic knowledge of statistics. 


PHYSICAL DEMANDS:

  • While performing the duties of this job, the individual is frequently required to sit and stand for long periods. The individual is occasionally required to walk; use hands and fingers to operate, handle, or feel objects, tools, or controls; reach with hands and arms. 
  • Up to 75% of the day may be spent at a lab bench.
  • There are aspects of the position’s duties that require a person in this role to work at heights above four (4) feet on occasion and move/lift up to 25 pounds.


WORK ENVIRONMENT:

  • Laboratory environment working with chemical reagents and performing some Biosafety Level 2 work. 
  • May involve handling of BSL-2 materials and organisms including human blood and/or blood products.
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