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R&D Scientist - Protein Purification
4basebio
Madrid, M
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What if your next job meant your work would directly power the future of synthetic DNA—and you could finally stop worrying about job stability?


That’s what you’ll find at 4basebio. Here, your contribution matters from day one. Your expertise in protein production will be at the heart of a company that’s shaping the biotech industry, with a team where people stay for years—because they want to.

4basebio is seeking a committed, adaptable and driven project manager to help scale up and adapt ongoing enzyme production processes due to expansion of the business.


Why will you want this role?

  • Direct impact: Your work will be critical for producing the enzymes that enable GMP-grade synthetic DNA manufacturing in the company´s UK facility.
  • Real stability: Most of our team members have been with us since 2008.
  • Competitive salary for the Spanish biotech market, plus restaurant vouchers and company-paid training.
  • True flexibility: Enjoy a hybrid model (60% onsite, 40% remote), adapt your working hours, and benefit from a genuinely supportive work environment.
  • International exposure: Be part of a global leader in synthetic DNA, collaborating with top-tier professionals from different backgrounds and countries.


What will you do?

  • Lead the production and purification of enzymes in GMP-like quality environments, optimizing and scaling processes from start to finish.
  • Ensure the successful technology transfer and scale-up of processes from laboratory to industrial production, maintaining compliance with ISO-9001 and supporting GMP standards.
  • Manage projects and teams, reporting directly to senior management.
  • Work closely with R&D and production, ensuring every protein batch meets the highest standards.
  • Drive continuous improvement as we expand and modernize our operations.


Who are you?

  • Degree or Master’s in Life Sciences (Biochemistry, Biotechnology, Chemistry, Biology, etc.).
  • PhD in Molecular Biology or similar is a strong plus.
  • Deep experience in protein over-expression and purification, process scale-up, and working under quality management systems (ISO 9001 required, GMP a bonus).
  • Team leadership skills, hands-on mentality, and a passion for applied biotechnology.
  • Excellent spoken and written English and Spanish.


Why now?

This position has become available because our previous colleague—who was trained and developed within our team—has decided to pursue a new professional opportunity abroad. This gives us the chance to find someone whose profile is fully aligned with our current focus: protein production, process scale-up, and quality.

If you’re looking to step into a role where your expertise will truly shape the future of our company, this is your moment.


Ready to make your science matter?

Send us your CV. To discuss the role in more depth, schedule a brief call with our recruiting manager at this link.


4basebio and Talento Científico are committed to equal opportunity and diversity in science.



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